Phil Klotzbach, who heads CSU'S Tropical Meteorology Project, has been watching Hurricane Matthew closely.

"I think the thing that is unusual about this storm is typically… storms that hit Florida during October, tend to hit the west coast of Florida.”

That was the last year a major hurricane – Category 3 or above – struck the U.S. mainland.

Matthew could now be the first since Dennis, Katrina, Rita and Wilma.

There have been no major strikes in the past 11 years -- almost 4,000 days.

Klotzbach says there are a few reasons no major storms have hit the U.S. in more than a decade.

"There have been storms out in the Atlantic," Klotzbach said. "They just haven't come ashore. We have an area of low pressure, which has helped take storms… out to sea.”

Matthew's current path is unpredictable, but it has already wreaked havoc on the islands.

Oct. 20, he says, is usually the time hurricane activity slows down dramatically.