The state's voters put the Colorado constitution in violation of federal statutes which make marijuana a controlled substance.
It's unclear how the U.S. justice department will respond.
Several members of Colorado's congressional delegation are waiting to hear U.S.
Attorney General Eric Holder's reaction before taking stances on potential alterations to federal law.
Rep. Diana DeGette (D) has already started legislation which would allow states to be exempted from federal laws against pot. Rep. Mike Coffman (R) told the Denver Post that he supports DeGette's bill despite his opposition to legalizing marijuana.
A similar bill was being crafted by Reps. Ed Perlmutter (D) and Jared Polis (D) to give Colorado an exception to federal laws on pot. Polis is a co-sponsor of DeGette's bill.
We got "wait and see" responses from Sens. Michael Bennet (D) and Mark Udall (D), who want to withhold their stances on changing federal law until after the justice department announces its intentions.
Rep. Scott Tipton (R) also wants to wait until he weighs in.
The only member of Colorado's delegation to say he opposes any change to federal law in response to Amendment 64 was Rep. Cory Gardner (R).
Rep. Doug Lamborn's (R) office did not return repeated requests for comment.
(KUSA-TV © 2012 Multimedia Holdings Corporation)