It was the 20th straight home win at Moby Arena for Colorado State (11-2).
Greg Smith and Wes Eikmeier each scored 11 points for the Rams.
Colorado State also had a 40-26 rebounding advantage, and outscored Adams State (7-1) 36-16 in the paint and 14-4 off turnovers.
John Jackson led Adams State with 17 points, and Kaimyn Pruitt grabbed 10 rebounds.
Adams State could only hit 29 percent of its field-goal attempts and was 6 of 16 from the free-throw line.
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