The Mustangs (2-0), a FCS school, improved their record to 4-12 against upper-division teams over the last 10 years. 

Wyoming (0-3), playing without injured quarterback Brett Smith, struggled offensively all day but led 15-14 at the half. 

Cal Poly reclaimed the lead, 21-15, on a 5-yard pass from Andre Broadous to Kristaan Ivory late in the third quarter. Bobby Zalud's 51-yard field goal with 9:49 left put the Mustangs up 24-15 and proved to be the difference.

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