Talent agency APA said Tuesday the Tony-winning Ebersole will play DiCaprio's mother in the drama.
Martin Scorsese is directing the film, based on a New York stockbroker's memoir of his rise and fall.
Ebersole, who also plays a mom in the TBS comedy "Sullivan & Son," is on the big screen next in "The Big Wedding" with Robert De Niro, Amanda Seyfried and Katherine Heigl. Ebersole is a two-time Tony winner for the Broadway musicals "Grey Gardens" and "42nd Street."
(Copyright 2012 by The Associated Press. All Rights Reserved.)