The fire has burned eleven structures, including four homes, near the town of Last Chance.
The large prairie fire is currently burning in southwestern Washington County, north of Highways 71 and 36.
Highway 71 from Limon to Brush remains closed.
The fast-moving blaze forced at least 25 residents out of their homes Monday near the town of Last Chance.
Automated evacuation calls were also sent out to homes around the town of Woodrow.
Those evacuation notices will remain in force until at least Tuesday morning, officials say.
Sharon Chenoweth, the wife of the Last Chance fire chief, evacuated along with her two grandchildren. She said the last she heard is that her home was still standing.
A Red Cross shelter was set up at the Akron High School Field House in Akron, located at 622 Elm Avenue.
Farmers and ranchers helped contain the fire. Three local residents braved the thick smoke and used tractors to plow the land in front of the blaze to create a break.
Firefighters are focusing on the northwest side of the fire. They fear the blaze may move closer to Woodlin School, which is located southeast of Woodrow.
Over 30 agencies are involved in battling the blaze, including air support.
Officials say the fire was started when a tire came loose from a passing car. Sparks from the tire's rim ignited the surrounding brush.