Adams finished with 18 points for UCLA (14-3, 4-0 Pac-12). Shabazz Muhammad added 14 and Kyle Anderson 12 for the Bruins, whose winning streak is their longest since a 10-game streak in 2008-09.
UCLA, coming off a season-low 57-point scoring output, improved to 6-1 all-time against the Buffaloes.
Spencer Dinwiddie led Colorado (11-5, 1-3) with 23 points. Josh Scott and Askia Booker had 18 each for the Buffaloes, losers of three of their last four.