Colorado State Patrol says it happened around 4:30 a.m. The driver was not injured.
The Colorado Department of Transportation says lane closures last through 1:30 p.m. as crews checked the bridge for safety.
One lane of 88th Avenue Westbound will remain closed for repairs.
CDOT did now say how long the closures will be in place.
Bridge engineers need to design the repairs and then CDOT will hire a contractor to complete the work.
A spokesperson for CDOT described the damage as, "significant."