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Gaither has a groin injury.

San Diego's other inactives are kicker Nate Kaeding, safety Brandon Taylor, cornerback Shareece Wright, linebacker Jonas Mouton, tackle Antonio Garay and tight end Ladarius Green.

For the Broncos, Chris Harris is expected to start at right cornerback for Tracy Porter.

Other Broncos inactives are quarterback Caleb Hanie, running back Knowshon Moreno, linebacker Steven Johnson, center C.J. Davis, tight end Julius Thomas and nose tackle Sealver Siliga.