If there was any doubt about the powerhouse in Colorado girls lacrosse, the past half-decade has put it to rest.

When Colorado Academy and Cherry Creek meet for girls lacrosse, it typically means the end of the school year is near because the two have played in the state championship game for five-straight seasons.

And every time the Mustangs have come away champions.

Wednesday night was no different as Colorado Academy captured its sixth title in program history with a 9-6 victory at the University of Denver, its fifth in a row.

"Each year we're a different team, and each year they're a different team. But the one thing that doesn't change is the competitive edge," senior captain Sloane Murphy said.

"We know Creek is going to bring all of their athleticism, all their speed, all their grit — and that was no exception this year."

The Mustangs scored four-straight goals to open the game and led the Bruins 6-2 at halftime.

Cherry Creek did its best to close the gap, but was unable to recover from the early deficit.

Colorado Academy was led by a game-high three goals from Ella Greene, and a pair by Murphy. Merrill Rollhaus, Maya Kendall, Jessie Bakes and Kendall Smart each contributed one goal.

Both Morgan Haws and Katie Collins scored twice for Cherry Creek, while Lily Assini had one goal.

"This win took a lot," Murphy said. "No matter offense or defense, we stepped up when we needed to and that's all you can ask for."

Colorado Academy's dominant run includes a 73-2 record over the past four seasons, both defeats to out-of-state opponents. The last time the Mustangs lost to an in-state opponent was against Mullen in early April 2015.

"This team is culture; it's family," Murphy said. "To be part of this program and to feel that culture in such a small school is super meaningful and super special."

Watch the extended video above and see the highlights on the 9NEWS Prep Rally this weekend.